While publishing the first topology, you may get an error when the topology builder attempts to enable to topology. Looking at the error it seems to suggest that the install cannot read the permissions on the Lync file share. In order to resolve this edit the file sharing permissions and add in the following groups giving them full control permissions to the share

• RTCHS Universal Services
• RTC Component Universal Services
• RTC Universal Server Admins
• RTC Universal Config Replicator

Re-publish the topology.